2016

Gerd Folkers, Martin Schmid (Hg.): Breakthroughs: Ideas at ETH Zurich that shaped the world. Chronos, Zürich 2016.

Gerd Folkers and Martin Schmid. Vitamin C – or the search for new diseases. In: Gerd Folkers, Martin Schmid (Hg.): Breakthroughs: Ideas at ETH Zurich that shaped the world. Chronos, Zürich 2016. S. 27 – 39.

Gerd Folkers, Helga Kessler Gesundheitsforschung bei komplexen Krankheiten. In: Irene Bopp-Kistler. Demenz. Rüffer & Rub, Zürich 2016 S. 466 – 483

Lino Guzzella & Gerd Folkers. Learn How to Learn to Think. Glion 2016

Gerd Folkers and Sabine Baier. A Continuum of Reproducible Research in Drug Development. In: Harald Atmanspacher, Sabine Maasen (Eds.) Reproducibility: Principles, Problems, Practices, and Prospects. Weinheim, Wiley S. 315 – 325

Gerd Folkers. Im Bergell zu Hause. Themenheft von Hochparterre 2106. S. 16

Gerd Folkers. 60 Jahre Industrie-Pharmazie: Historischer Wandel in Lehre und Forschung. (Durch)brüche, die die Pharmazie veränderten. SWISS PHARMA 39 (2016) S. 25 – 29

Amrei Wittwer und Gerd Folkers. Schmerz. Innenansichten eines Patienten und was die Wissenschaft dazu sagt. Stuttgart, Hirzel 2016

Amrei Wittwer, Peter Krummenacher, Roberto La Marca, Ulrike Ehlert, Gerd Folkers,
Salivary Alpha-Amylase Correlates with Subjective Heat Pain Perception. Pain Medicine 2016. P. 1-6

K. Grüntzig, R. Graf, G. Boo, §, F. Guscetti, M. Hässig, K.W. Axhausen, S. Fabrikant, M. Welle, D. Meier, G. Folkers, A. Pospischil. Swiss Canine Cancer Registry 1955–2008: Occurrence of the Most Common Tumour Diagnoses and Influence of Age, Breed, Body Size, Sex and Neutering Status on Tumour Development. J. Comp. Path. 2016, 155, 1-15

2015

Gerd Folkers. Der Gesundheits-Gault-Millau – ein Reiseführer von und für Patienten durch die Galaxis des schweizerischen Gesundheitssystems, in: Stephan Sigrist, Nicolas Bornstein, Kristiani Lesmono, Andrea Sybilla Dür, Gerd Folkers. Hacking HealthCare. Das Gesundheitssystem verstehen und Weiterdenken. Zürich, W.I.R.E. & NZZ Libro (2015) S. 421 – 422

Stephan Sigrist, Nicolas Bornstein, Kristiani Lesmono, Andrea Sybilla Dür, Gerd Folkers. Hacking HealthCare. Das Gesundheitssystem verstehen und Weiterdenken. Zürich, W.I.R.E. & NZZ Libro (2015)

R. Graf, K. Grüntzig, M. Hässig, K.W. Axhausen, S. Fabrikant, M. Welle, D. Meier, F. Guscetti, G. Folkers, V. Otto, A. Pospischil. Swiss Feline Cancer Registry: A Retrospective Study of the Occurrence of Tumours in Cats in Switzerland from 1965 to 2008, Journal of Comparative Pathology, 153, 2015, 266-277

K. Grüntzig, R. Graf, M. Hässig, M. Welle, D. Meierx, G. Lott, D. Erni, N. S. Schenker, F. Guscetti, G. Book, K. Axhausen, S. Fabrikant, G. Folkers and A. Pospischil.
The Swiss Canine Cancer Registry: A Retrospective Study on the Occurrence of Tumours in Dogs in Switzerland from 1955 to 2008, J. Comp. Path. 2015, 152, 161-171

Jannis Wernery, Harald Atmanspacher, Jürgen Kornmeier, Victor Candia, Gerd Folkers, Marc Wittmann, Temporal processing in bistable perception of the Necker cube. Perception, 2015, volume 44, pages 0000–0000 doi:10.1068/p7780

2014

Simone Achermann, Stephan Sigrist, Burkhard Varnholt, Michele Wannaz und Gerd Folkers Was zählt – 2014. Suhrkamp Taschenbuch 4462, Berlin 2013

Gerd Folkers, Martin Schmid (Hg.): IdEAS – ETH Zurich: Where Context Favors Innovation. Chronos Zürich 2014

Gerd Folkers. Ein gelber verschneiter Hund erregt kein Mitleid und zur Beschreibung der Welt fehlt wenigstens noch das Dreieck: Gerd Folkers asssoziiert Céline Meyrats Bilderwelten. In: In Bildern denken. Ein Experiment über die Wahrnehmung von Bildern. Hochschule Luzern, 2014

Gerd Folkers and Martin Schmid. An Eternal Vision. In: Gerd Folkers, Martin Schmid (Hg.): IdEAS – ETH Zurich: Where Context Favors Innovation. Chronos Zürich 2014 S. 93 – 104.

Gerd Folkers. Ein Reiseführer durch die Galaxis des Schweizerischen Gesundheitssystems – Versuch einer Utopie. In: Andrea Dür, Kristiani Lesmono, Nicholas Bornstein, Gerd Folkers, Stephan Sigrist Gesundheit verstehen und weiterdenken, Fakten und Ideen für das Gesundheitssystem im 21. Jahrhundert. Zürich, NZZ Libro (2014)

H. Atmanspacher, L. Bezzola Lambert, G. Folkers and P. A. Schubiger, Relevance relations for the concept of reproducibility. J. R. Soc. Interface 2014 11, 20131030.

Karin Landolt, Amrei Wittwer, Thomas Wyss, Lui Unterassner, Wolfgang Fach, Peter Krummenacher, Peter Brugger, Helene Haker, Wolfram Kawohl, Pius August Schubiger, Gerd Folkers and Wulf Rössler, Help-seeking in people with exceptional experiences: results from a general population sample. Front. Public Health, 21 May 2014 | doi: 10.3389/fpubh.2014.00051

Jan A. Hiss, Michael Reutlinger, Christian P Koch, Anna M Perna, Petra Schneider, Tiago Rodridues, Sarah Haller, Gerd Folkers, Lutz Weber, Renato B Baleeiro, Peter Walden, Paul Wrede & Gisbert Schneider, Combinatorial chemistry by ant colony optimization. Futur Med Chem. 6, (2014) 267 – 280.

Vladimir Pliska, Gerd Folkers, Vojtech Spiwok, Thermodynamics of the interaction between oxytocin and its myometrial receptor in sheep: A stepwise binding mechanism Biochemical Pharmacology 91 (2014) 119–127

Pospischil A, Folkers G. How much reproducibility do we need in human and veterinary pathology? Exp Toxicol Pathol (2014), http://dx.doi.org/10.1016/j.etp.2014.11.005

2013

Raimund Mannhold, Hugo Kubinyi, Gerd Folkers (Hrsg.) Methods and Principles in Medicinal Chemistry, Vol. 15 ( 2002) – Vol. 55 (2013), Wiley-VCH, Weinheim.

Gerd Folkers. Die Transformation des Ich im Laboratorium. In: Michael Mettler & Ladina Bezzola ( Hg.) Ortlose Mitte. Das ICH als kulturelle Hervorbringung. Wallstein 2013. S. 102 – 118.

Gerd Folkers. Der Sinn des Begreifens. In: Simone Achermann, Stephan Sigrist, Burkhard Varnholt, Michele Wannaz und Gerd Folkers, Was zählt – 2014. Suhrkamp Taschenbuch 4379, Berlin 2013. S. 98-104.

Gerd Folkers. Menschenbildgebungsverfahren. In: Wulf Rössler & Hans Danuser (Hg.), Burg aus Holz – das Burghölzli. Von der Irrenheilanstalt zur Psychiatrischen Universitätsklinik Zürich. Entwicklungen, Innen- und Aussensichten. NZZ Libro 2013.

Gerd Folkers. Von Sex, Individualität und Tod. In: Evolution – Szenarien für den Menschen der Zukunft, Abstrakt No 10. S. 78 – 86, 2013

Gerd Folkers NZZ, Sechs Thesen zur Typologie. Sonderbeilage Bildung und Erziehung 11, 11. September 2013

Gerd Folkers. Wie funktioniert Science Fiction. In: Rainer Egloff und Martin Schmid (Hg.): Future Reloaded: Zukunftsvisionen in Wissenschaft und Science-Fiction. Collegium Helveticum Heft 13, Zürich: Collegium Helveticum 2013

V. Pliska, G. Folkers, Chemistry and chemists in the story of insulin [Inzulín:chemie a chemici v jeho historii], Diabetologie Metabolismus Endokrinologie Vyziva 15 (2), pp. 111–118.

Peter Krummenacher, Elvan Kut, Gerd Folkers, Peter Brugger. Naloxone modulates visual judgments of similarity but not dissimilarity. Cognitive, Affective, & Behavioral Neuroscience, March 2013, DOI 10.3758/s13415-013-0155-9

Gerd Folkers, Freiheit in der Forschung, Die Pharmazie 7, An International Journal of Pharmaceutical Sciences, Volume 68, July 2013

Gerd Folkers, Economization in Science and of Science itself: Changes to the Game, Swiss Science and Technology Council Report 4/2013, 42-44, 2013

2012

Simone Achermann, Stephan Sigrist, Burkhard Varnholt, Michele Wannaz und Gerd Folkers Was zählt – 2013. Suhrkamp Taschenbuch 4379, Berlin 2012

Gerd Folkers. Das Immunsystem im Computer. Vögele Kultur Bulletin 92 2012, S. 14-15.

Gerd Folkers, Kann das Partikel die Frage verstehen? In: Irene Weingartner, Aufzeichnungsmaschine. Edition clandestine, Biel 2012, S. 26-28

Johannes Fehr & Gerd Folkers, Visionen eines Grandseigneurs, in: Weggefährten, hrsg. Von Donimk Galliker, Academia Engelberg 2012, S. 31 -34.

Gerd Folkers, Drug Design and Emotion SWISS PHARMA 33 (2011) S. 11 – 14

Gerd Folkers. On future challenges of global Pharma. What are the core issues, role models and how to find or educate people with the right competencies? A synopsis of the panel discussion. SWISS PHARMA 34 (2012) s. 37 – 39

Gerd Folkers, Wissenschaft in Gefahr „Den Fressnapf der Forscher verschoben“ Spiegel-Online, 10.10.2012 http://www.spiegel.de/wissenschaft/medizin/forschung-warum-der-utilitarismus-die-freiheit-der-forschung-bedroht-a-860141.html

Gerd Folkers, Protein-Protein-Interactions, Preface. Methods in Medicinal Chemistry Wiley-VCH, 2012

Schaffner N, Folkers G, Käppeli S, Musholt M, Hofbauer GFL, et al. (2012) A New Tool for Real-Time Pain Assessment in Experimental and Clinical Environments. PLoS ONE 7(11): e51014. doi:10.1371/journal.pone.0051014

2011

Gerd Folkers. Von der Umkehrung der Pyramide. – Menschenbilder in Medizin und Pharmazie. In: Rainer Egloff, Priska Gisler, Beatrix Rubin (Hg.): Modell Mensch –Konturierungen des Menschlichen in den Wissenschaften, Edition Collegium Helveticum, Band 7, Chronos Verlag, Zürich 2011. S. 199 – 219

Gerd Folkers. Der Horizont im Kopf. Grenzen als Orte der Identitätsfindung. In: Grenzen. Was sie auslösen und wie wir mit ihnen umgehen. Schritte ins Offene. 2/2011, S. 4–7

Gerd Folkers. Forschung und Gesellschaft in der Zukunft. In: Agenda 2010 – II Schweiz – Europa. Bildung, Forschung, Innovation – Der Industriestandort Schweiz in Europa und der Welt. Europa Forum Luzern (Hg.). Luzern 2011, S. 117–127.

Gerd Folkers. Standgericht für Iseblitz. Abstract, 1, 2011. S.62 – 63

Gerd Folkers. Vom Wert der Flohmärkte. Abstract, 2, 2011. S.60 – 61

Gerd Folkers. Die Gesellschaft miteinbeziehen. ID-E Berlin – International Dialogue on Education, 12/2011, S. 12–13.

Jair Stern, Victor Candia, Roseline I. Porchet, Peter Krummenacher, Gerd Folkers, Manfred Schedlowski, Dominik A. Ettlin, Georg Schönbächler: Placebo-mediated, Naloxone-sensitive suggestibility of short-term memory performance, Neurobiology of Learning and Memory, 2011, 95, 326-334

Elvan Kut, Victor Candia, Jan von Overbeck, Judit Pok, Daniel Fink, Gerd Folkers Pleasure-Related Analgesia Activates Opioid-Insensitive Circuits, The Journal of Neuroscience, 2011, 31, 4148-4153;

Wulf Rössler, Gerd Folkers, Der Patient im Mittelpunkt – das Geld im Vordergrund, Schweizerische Ärztezeitung, 2011;92: 48, 1881–1883

Gerd Folkers, Samuel Zinsli: Bildeffekte in wissenschaftstheoretischer Perspektive In: Präsenz im Entzug – Ambivalenzen des Bildes, hg. von Philipp Stoellger und Thomas Klie, Mohr Siebeck 2011.

Gerd Folkers: Duchamp und die Poincaré-Vermutung, In: Margarete Jarchow (Hg.), Kreativität in Gestaltungsprozessen, Schriften des Graduiertenkollegs – KUNST UND TECHNIK, Band 3, Neumünster 2011, S. 111–130.

2010

Gerd Folkers Boyer, Martin/ Vychitil, Pavel/ Pliska, Vladimir (Hrsgg.): The Role of Anthropocentrism in Science. 11th Villa Lanna Meeting on «Science, or Else?», Prague, January 16–18, 2009, Zürich 2010 (= Collegium Helveticum Heft ; 10)

Gerd Folkers Egloff, Rainer/ Fehr, Johannes (Hrsgg.): Pragmatik der Gefühle,  Zürich 2010.
(= Edition Collegium Helveticum ; 6) Ca. 130 S. Loseblattsammlung in Blechbüchse

Gerd Folkers. Ein Colloquium der Dinge. In: Hans Danuser. Ein Colloquium der Dinge. Ein „Kunst in Architektur“ – Projekt von Hans Danuser in der Semper-Sternwarte. Collegium Helveticum 2010. S. 12-22.

Gerd Folkers. Piraterie ist eine Frage des Standpunkts. In: Piraten. Zur modernen Freibeuterei (= Abstracts 2010/1), S.37-39

Gerd Folkers. Interdisziplinär forschen, aber wie? Horizonte. März 2010 S.33

Gerd Folkers. Neuland. Künste und Wissenschaften im Dialog. Zett. 1, 2010 S.14-16

Gerd Folkers. Arzneimittel vom Reissbrett. In: online academy – Das interaktive FPH-Fortbildungsprogramm in Offizin- und Spitalpharmazie, Nr. 2, 2010

Christoph Blaufelder, Stephan Sigrist, Burkhard Varnholt, Gerd Folkers. Domino. Handbuch für eine nachhaltige Welt. Zürich, Neue Zürcher Zeitung & Frankfurter Allgemeine Buch (2010)

Krummenacher, P., Candia, V., Folkers, G., Schedlowski, M., Schönbächler, G. Prefrontal cortex modulates placebo analgesia (2010) Pain, 148 (3), pp. 368-374.

Gerd Folkers. Arzneimittel vom Reissbrett. Online academy. 2 2010 S. 36-45

Gerd Folkers. Roadside Picnic – From Anthropocentrism to Anthropomorphism, an Attitude for Human Survival, or How to Make you Feel at Home in Universe. In: Folkers, Gerd/ Boyer, Martin/ Vychitil, Pavel/ Pliska, Vladimir (Hrsgg.): The Role of Anthropocentrism in Science. 11th Villa Lanna Meeting on «Science, or Else?», Prague, January 16–18, 2009, Zürich 2010 (= Collegium Helveticum Heft ; 10), S.43-54

Gerd Folkers, Elvan Kut, and Martin Boyer. Drug Design: Designer Drugs. In: S. Konsorski-Lang and M. Hampe (Hrsg.) The Design of Material, Organism, and Minds, Springer Berlin, Heidelberg 2010. S. 53-63

M. Kusserow, G. Tröster, V. Candia, G. Folkers, O. Amft, H. Hildebrandt, Wearable monitoring of stage fright in professional musicians, Wearable Computers (ISWC), 2010 International Symposium, 10-13 Oct. 2010, DOI: 10.1109/ISWC.2010.5665852

2009

Gerd Folkers. Vom Schattenwurf der Moleküle. In: Ingolf Dalferth, Phillip Stoelllger und Andreas Hunziker (Hg.) Unmöglichkeiten. Religion Philosophy and Theology. Mohr Siebeck, Tübingen 2009 S. 139 – 159.

Gerd Folkers “…dein Schmerz, dessen Macht über Unglückliche doch nichts übertrifft.” Revue Economique et Sociale, Volume 67, Juin 2009, S. 27ff.

Gerd Folkers*, Vivianne Otto, “Qualität ist nicht messbar – Quantifizierung und multilaterale Übereinkünfte als Surrogate” Swiss Pharma 31 (Oktober 2009) Nr. 9, S. 19ff.

Peter Krummenacher, Victor Candia, Gerd Folkers, Manfred Schedlowski und Georg Schönbächler*
“Prefrontal cortex modulates placebo analgesia,” Pain, doi:10.1016/j.pain.2009.09.033

2008

Gerd Folkers Wittwer, Amrei/Kut, Elvan/Pliska, Vladimir (Hgg.): Reproducibility – Arts, Science, and Living Nature – 10th Villa Lanna Meeting on «Science, or Else?», Prague. January 11–13, 2008. Zürich 2008 (=Collegium Helveticum Heft ; 5)

Gerd Folkers. Wie geht Kultur «unter die Haut»? Die Sicht des Apothekers auf die Kultur der Arznei. In: Niewöhner, Jörg/Kehl, Christoph/Beck, Stefan (Hgg.): Wie geht Kultur unter die Haut? Emergente Praxen an der Schnittstelle von Medizin, Lebens- und Sozialwissenschaft, Bielefeld 2008

Gerd Folkers: Ziehen wir in den Krieg? Was trojanische Pferde, Immunsysteme und künstliche Intelligenz verbindet. Wieweit trägt die Parallele von Informationstechnologie und Biologie? GDI- Impuls. Wissensmagazin für Wirtschaft, Gesellschaft, Handel, 1, 2008 44-49

Mind the Future – Kompendium für Gegenwartstrends. Stephan Sigrist, Burkhard Varnholt, Simone Achermann, Gerd Folkers. Zürich, Neue Zürcher Zeitung (2008) 2 editions

Schaffner, N., Wittwer, A., Kut, E., Folkers, G., Benninger, D.H., Candia, V. Heat pain threshold and tolerance show no left-right perceptual differences at complementary sites of the human forearm (2008) Neuroscience Letters, 440 (3), pp. 309-313

Wie geht Kultur «unter die Haut»? Die Sicht des Apothekers auf die Kultur der Arznei In: Niewöhner, Jörg/Kehl, Christoph/Beck, Stefan (Hrsg.): Wie geht Kultur unter die Haut? Emergente Praxen an der Schnittstelle von Medizin, Lebens- und Sozialwissenschaft, Bielefeld 2008

Petra Kapkova, Vildan Alptuzun, Eberhard Heller, Eva Kugelmann, Gerd Folkers and Ulrike Holzgrabe. “Strategies for Development of New Lead Structures for Inhibition of Acetylcholinesterase” Chemistry and Molecular Aspects of Drug Design and Action, 2008

erd Folkers “Über kluge Bemerkungen.” Hermeneutische Blätter 1/2, 2008.

2007

Gerd Folkers Egloff, Rainer/Michel, Matthias (Hgg.): Archäologie der Zukunft, Zürich 2007 (=Edition Collegium Helveticum ; 3)

Gerd Folkers Wittwer, Amrei/Kut, Elvan/Pliska, Vladimir (Hgg.): Approaching Scientific Knowledge: Metaphors and Models – 9th Villa Lanna Meeting on «Science, or Else?», Prague. January 12 – 14, 2007, Zürich 2007 (=Collegium Helveticum Heft ; 4)

Gerd Folkers. Schmerz. Aspekte der Physiologie und Therapie.in: Georg Schönbächler (Hg.): Schmerz, Edition Collegium Helveticum Bd. 4, Zürich: Chronos Verlag 2007

Gerd Folkers, Ist Vorbeugen besser als Heilen? In: Grenzen aufheben – Thesen zur Zukunft der Ausbildung für Gesundheitsberufe, Stiftung Careum, 2007

Gerd Folkers, «Die Wurst-Knäcke-Sushi-Theorie des Automobilbaus» persönlich – Die Zeitschrift für Unternehmensführung, Marketing und Kommunikation, Januar u. Februar 2007

David Bosshart, Gerd Folkers und Peter Wippermann, «Der Gegenblick des Menschen – ein Gespräch», Gespräch: Stefan Kaiser GDI für Wirtschaft und Gesellschaft – Bang: Die Zukunft der Evolution 2007

Gerd Folkers. Anything New Under the Sunspots? Collegium Helveticum 2007.

Huber, R.D., Gao, B., Pfändler, M.-A.S., Zhang-Fu, W., Leuthold, S., Hagenbuch, B., Folkers, G., Meier, P.J., Stieger, B. Characterization of two splice variants of human organic anion transporting polypeptide 3A1 isolated from human brain (2007) American Journal of Physiology – Cell Physiology, 292 (2), pp. C795-C806.

Iqbal, J., Scapozza, L., Folkers, G., Müller, C.E. Development and validation of a capillary electrophoresis method for the characterization of herpes simplex virus type 1 (HSV-1) thymidine kinase substrates and inhibitors (2007) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 846 (1-2), pp. 281-290.

Kut, E., Schaffner, N., Wittwer, A., Candia, V., Brockmann, M., Storck, C., Folkers, G. Changes in self-perceived role identity modulate pain perception (2007) Pain, 131 (1-2), pp. 191-201.

Folkers, G., Wittwer, A. Drug design and emotion (2007) AIP Conference Proceedings, 958, pp. 3-8.

2006

Gerd Folkers Kut, Elvan/Wittwer, Amrei/Pliska, Vladimir (Hgg.): Promises of Science: 8th Villa Lanna Meeting on «Science, or Else?», Prague. January 13 – 15, 2006, Zürich 2006 (=Collegium Helveticum Heft ; 3)

Eberle, A.N., Wennemers, H., Nayler, O., Ernst, B., Folkers, G., Pliska, V., Bürgisser, E. Journal of Receptors and Signal Transduction: Preface (2006) Journal of Receptors and Signal Transduction, 26 (5-6), pp. 359-360.

Gerd Folkers Killer-Maps? – Mind-Maps! GDI Impuls – Wissensmagazin für Wirtschaft, Gesellschaft, Handel, März 2006, 100-102

Gerd Folkers Placebotion, GDI Impuls – Wissensmagazin für Wirtschaft, Gesellschaft, Handel, Juli 2006 35-37

Petra Kapková, Eberhard Heller, Eva Kugelmann, Johan Faber, Gerhard Bringmann, Ulrich Kessler, Gerd Folkers, Ulrike Holzgrabe, “Random chemistry as a new tool for the generation of small-compound libraries.” Archiv der Pharmazie. 10/2006; 339(9):489-97.

Lack G, Homberger-Zizzari E, Folkers, G., Scapozza, L., Perozzo R. Recombinant expression and biochemical characterization of the unique elongating beat-ketoacyl-acyl carrier protein synthase involved in fatty acid biosynthesis of oPlasmodium falciparum using natural and artificial substrates. J. Biol Chem 2006 April 7, 281 (14): 9538-46

Limacher A., Kloer DP., Fluckiger S., Folkers, G., Cramery R., Scapozza, L., The crystal structure of Aspergillus fumigatus cyclophilin reveals 3D domain swapping of a central element. Structure 2006 Feb, 14 (2): 185-95

Birringer, M.S., Perozzo, R., Kut, E., Stillhart, C., Surber, W., Scapozza, L., Folkers, G. High-level expression and purification of human thymidine kinase 1: Quaternary structure, stability, and kinetics (2006) Protein Expression and Purification, 47 (2), pp. 506-515.

Otto, V.I., Damoc, E., Cueni, L.N., Schürpf, T., Frei, R., Ali, S., Callewaert, N., Moise, A., Leary, J.A., Folkers, G., Przybylski, M. N-Glycan structures and N-glycosylation sites of mouse soluble intercellular adhesion molecule-1 revealed by MALDI-TOF and FTICR mass spectrometry (2006) Glycobiology, 16 (11), pp. 1033-1044.

Folkers, G., Ishai, A., Rudin, M., Schubiger, P.A., Bräutigam, M., Möhler, H., Märki, H.P. Imaging in biomedical research: Mini-Symposium of the Division for Medicinal Chemistry (DMC) of the Swiss Chemical Society (SCS), at the Department of Chemistry, University of Basel, May 18, 2006 (2006) Chimia, 60 (11), pp. 805-814.

2005

Gerd Folkers Tomorrow People of Yesterday I: Die Erfindung des iPod, GDI Impuls – Wissensmagazin für Wirtschaft, Gesellschaft, Handel, 2.05, 2005

Gerd Folkers, Trading-up-Travelling: Vom Luxus der Langsamkeit, GDI Impuls – Wissensmagazin für Wirtschaft, Gesellschaft, Handel, 3.2005

Gerd Folkers, I, Robot – Wir, Menschen, GDI Impuls – Wissensmagazin für Wirtschaft, Gesellschaft, Handel, Winter 2005, 95-99

Yvonne Meier, Marzia Cavallaro Malgorzata Roos, Christiane Pauli-Magnus, Gerd Folkers, Peter J. Meier and Karin Fattinger. Incidence of drug-induced liver injury in medical inpatients. European Journal of Clinical Pharmacology 61, 135-143 (2005)

Hofstetter,B., Vuong,V., Folkers, G., Pruschy, M. Patupilone acts as radiosensitizing agent in multidrug-resistant cancer cells in vitro and in vivo. Clin Cancer Res 11, 1588-96 (2005).

Yarim, M., Moro S., Huber R., Folkers G. Application of QSAR analysis to organic anion transporting polypeptide 1a5 (Oatp1a5) substrates. Bioorg Med Chem 13, 463-71 (2005).

Chris de Graaf, Pavel Pospisil, Wouter Pos, Gerd Folkers, and Nico P. E. Vermeulen*, Binding Mode Prediction of Cytochrome P450 and Thymidine Kinase. Protein-Ligand Complexes by Consideration of Water and Rescoring in Automated Docking J. Med. Chem. 48, 2308-2318 2005

Birringer, M.S., Claus, M.T., Folkers, G., Kloer, D.P., Schulz, G.E., Scapozza, L. Structure of a type II thymidine kinase with bound dTTP (2005) FEBS Letters, 579 (6), pp. 1376-1382.

Kostrewa, D., Winkler, F.K., Folkers, G., Scapozza, L., Perozzo, R. The crystal structure of PfFabZ, the unique β-hydroxyacyl-ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum (2005) Protein Science, 14 (6), pp. 1570-1580

Bertschi, I., Collomb, M., Rist, L., Eberhard, P., Sieber, R., Bütikofer, U., Wechsler, D., Folkers, G., Von Mandach, U. Maternal dietary alpine butter intake affects human milk: Fatty acids and conjugated linoleic acid isomers (2005) Lipids, 40 (6), pp. 581-587.

Lerch, M., Kamimori, H., Folkers, G., Aguilar, M.-I., Beck-Sickinger, A.G., Zerbe, O. Strongly altered receptor binding properties in PP and NPY chimeras are accompanied by changes in structure and membrane binding (2005) Biochemistry, 44 (25), pp. 9255-9264.

Kapková, P., Heller, E., Unger, M., Folkers, G., Holzgrabe, U. Random chemistry as a new tool for the generation of small compound libraries: Development of a new acetylcholinesterase inhibitor (2005) Journal of Medicinal Chemistry, 48 (23), pp. 7496-7499.

2004

Gerd Folkers. Die Laborbecherkultur, Winterthur, Corvus (2004)

Didier Rognan, Matthias J. Reddehase, Ulrich H. Koszinowski, Gerd Folkers Molecular modeling of an antigenic complex between a viral peptide and a class I major histocompatibility glycoprotein. Proteins: Structure, Function, and Bioinformatics 13 70 – 85 (2004)

Frank Altznauer, Sébastien Conus, Andrea Cavalli, Gerd Folkers, and Hans-Uwe Simon, Calpain-1 Regulates Bax and Subsequent Smac-dependent Caspase-3 Activation in Neutrophil Apoptosis, J. Biol. Chem. 279, 5947-5957 (2004)

Gonser, S., Crompton, N. E., Folkers, G., Weber, E. Increased radiation toxicity by enhanced apoptotic clearance of HL-60 cells in the presence of the pentapeptide thymopentin, which selectively binds to apoptotic cells. Mutat Res 558, 19-26 (2004).

Perozzo, R., Folkers, G., Scapozza, L. Thermodynamics of protein-ligand interactions: history, presence, and future aspects. J Recept Signal Transduct Res 24, 1-52 (2004).

Spiwok, V., Jakusch, M., Pospisil, P., Folkers, G., Pliska, V. Molecular modelling study of free-energy landscape of oxytocin and atosiban. J Pept Sci 10 (2004).

Cavalli, A., Prota, A., Folkers, G., Scapozza, L. A molecular dynamics study of reovirus attachment protein sigma1 reveals conformational changes in sigma1 structure. Biophys J 86, 3423-31 (2004).

Otto, V. I., Schurpf, T., Folkers, G., Cummings, R. D. Sialylated complex-type N-glycans enhance the signaling activity of soluble intercellular adhesion molecule-1 in mouse astrocytes. J Biol Chem 279, 35201-9 (2004).

Pospisil, P., Folkers, G. Making the best account of molecular docking in drug design (2004) Fabad Journal of Pharmaceutical Sciences, 29 (2), pp. 81-92.

Folkers, G. Pharmaceutical Chemistry at the ETH Zürich (2004) Chimia, 58 (10), pp. 707-710.

Raić-Malić, S., Johayem, A., Ametamey, S.M., Batinac, S., De Clercq, E., Folkers, G., Scapozza, L. Synthesis, 18F-radiolabelling and biological evaluations of C-6 alkylated pyrimidine nucleoside analogues (2004) Nucleosides, Nucleotides and Nucleic Acids, 23 (11), pp. 1707-1721.

2003

Molecular Modeling von Hans-Dieter Höltje, Wolfgang Sippl, Didier Rognan und Gerd Folkers, Weinheim, Wiley-VCH (2003) 5 editions

Molecular Biology in Medicinal Chemistry. Theo Dingermann, Dieter Steinhilber und Gerd Folkers, Weinheim, Wiley-VCH (2003)

Gerd Folkers Hanser, Christof/Tran, Van Van: Vireal Lab – eine innovative, multimediale Lern-und Arbeitsumgebung, Switch Journal 2/2002 S.32-34

Folkers, G., Kessler, U. Random chemistry: Look for the unexpected (2003) Current Drug Discovery, (JAN.), pp. 33-36.

Lichtsteiner, S., Rizzotti, S., Weber, C., Vögtli, A., Burkhart, H., Neier, R., Van Khov-Tran, V., Folkers, G., Ernst, B. Pharmasquare (Pharma2) (2003) Chimia, 57 (3), pp. 116-120.

Folkers, G., Kubinyi, H., Hoffmann, R., Langer, T., Scapozza, L., Johner, R., Ballmer, P., Jahnke, W. Focal point: Medicinal chemistry: A. Ligand-receptor interactions: From understanding to design (2003) Chimia, 57 (1-2), pp. 57-59.

Khov-Tran, V.V., Hanser, C.F.W., Folkers, G. Vireal Lab – From instruction to construction (2003) Chimia, 57 (3), pp. 121-127

Folkers, G., Pliska, V., Birringer, M. Structure and effect of drugs – Where is the relationship? [Struktur und wirkung – Wo ist die beziehung?] (2003) Deutsche Apotheker Zeitung, 143 (10), pp. 52-56.

Dahinden, A., Rau, K., Schmidt, R., Folkers, G. Pathways to a new pharmaceutical total quality. Part 4: Quality costs and enterprise resource planning systems [Wege zu einer neuen pharmazeutischen ‚total quality‘. Teil 4: Qualitätskosten und enterprise resource planning system] (2003) Pharmazeutische Industrie, 65 (1), pp. 13-20.

Spadola, L., Novellino, E., Folkers, G., Scapozza, L. Homology modelling and docking studies on Varicella Zoster Virus Thymidine kinase (2003) European Journal of Medicinal Chemistry, 38 (4), pp. 413-419.

Folkers, G., Otto, M. Pharma nation network AG – CME online (2003) Chimia, 57 (6), pp. 345-348.

Džolić, Z., Cetina, M., Kovaček, D., Hergold-Brundić, A., Mrvoš-Sermek, D., Nagl, A., Slade, N., Pavelić, K., Balzarini, J., De Clercq, E., Zerbe, O., Folkers, G., Scapozza, L., Mintas, M. Molecular structures and ab initio molecular orbital calculations of the optically active derivatives of 1-aminocyclopropane-1-carboxylic acid (2003) Journal of Molecular Structure, 655 (2), pp. 229-241.

Russ, P., Schelling, P., Scapozza, L., Folkers, G., De Clercq, E., Marquez, V.E. Synthesis and Biological Evaluation of 5-Substituted Derivatives of the Potent Antiherpes Agent (north)-Methanocarbathymine (2003) Journal of Medicinal Chemistry, 46 (23), pp. 5045-5054.

Klein, C.D.P., Schiffmann, R., Folkers, G., Piana, S., Röthlisberger, U. Protonation States of Methionine Aminopeptidase and Their Relevance for Inhibitor Binding and Catalytic Activity (2003) Journal of Biological Chemistry, 278 (48), pp. 47862-47867.

Pospisil, P., Ballmer, P., Scapozza, L., Folkers, G. Tautomerism in Computer-Aided Drug Design (2003) Journal of Receptors and Signal Transduction, 23 (4), pp. 361-371.

Van Tran, V., Lichtsteiner, S., Ernst, B., Otto, M., Folkers, G. Towards a virtual education in pharmaceutical sciences. An innovative E-learning approach. (2003) Current problems in dermatology, 32, pp. 43-51.

Prekupec, S., Svedružić, D., Gazivoda, T., Mrvoš-Sermek, D., Nagl, A., Grdiša, M., Pavelić, K., Balzarini, J., De Clercq, E., Folkers, G., Scapozza, L., Mintas, M., Raić-Malić, S. Synthesis and Biological Evaluation of Iodinated and Fluorinated 9-(2-Hydroxypropyl) and 9-(2-Hydroxyethoxy)methyl Purine Nucleoside Analogues (2003) Journal of Medicinal Chemistry, 46 (26), pp. 5763-5772.

Pizzagalli, F., Varga, Z., Huber, R.D., Folkers, G., Meier, P.J., St.-Pierre, M.V. Identification of steroid sulfate transport processes in the human mammary gland (2003) Journal of Clinical Endocrinology and Metabolism, 88 (8), pp. 3902-3912.

2002

Eberle, A.N., Folkers, G., Pliska, V., Bürgisser, E. 9th Swiss workshop of methodology in receptor research Zürich, September 23-26, 2001; Preface (2002) Journal of Receptors and Signal Transduction, 22 (1-4), pp. xi-xii.

Sulpizi, M., Folkers, G., Rothlisberger, U., Carloni, P., Scapozza, L. Applications of density functional theory-based methods in medicinal chemistry (2002) Quantitative Structure-Activity Relationships, 21 (2), pp. 173-181.

Lerch, M., Gafner, V., Bader, R., Christen, B., Folkers, G., Zerbe, O. Bovine pancreatic polypeptide (bPP) undergoes significant changes in conformation and dynamics upon binding to DPC micelles (2002) Journal of Molecular Biology, 322 (5), pp. 1117-1133.

Pospisil, P., Kuoni, T., Scapozza, L., Folkers, G. Methodology and problems of protein-ligand docking: Case study of dihydroorotate dehydrogenase, thymidine kinase, and phosphodiesterase 4 (2002) Journal of Receptors and Signal Transduction, 22 (1-4), pp. 141-154.

Klein, C.D.P., Folkers, G. Understanding the Selectivity of Fumagillin for the Methionine Aminopeptidase Type II (2002) Oncology Research, 13 (12), pp. 513-520.

Dahinden, A., Schmidt, R., Folkers, G. Towards a new pharmaceutical total quality. Part 1: Good manufacturing practice (GMP) is not the same as total quality [Wege zu einer neuen pharmazeutischen, ‚total quality‘: Teil 1: Good manufacturing practice (GMP) ist nicht gleich, ‚total quality‘] (2002) Pharmazeutische Industrie, 64 (10), pp. 1027-1033.

Otto, V.I., Gloor, S.M., Frentzel, S., Gilli, U., Ammann, E., Hein, A.E., Folkers, G., Trentz, O., Kossmann, T., Morganti-Kossmann, M.C. The production of macrophage inflammatory protein-2 induced by soluble intercellular adhesion molecule-1 in mouse astrocytes is mediated by src tyrosine kinases and p42/44 mitogen-activated protein kinase (2002) Journal of Neurochemistry, 80 (5), pp. 824-834.

Pizzagalli, F., Hagenbuch, B., Stieger, B., Klenk, U., Folkers, G., Meier, P.J. Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter (2002) Molecular Endocrinology, 16 (10), pp. 2283-2296.

Lerch, M., Gafner, V., Bader, R., Christen, B., Folkers, G., Zerbe, O. Bovine pancreatic polypeptide (bPP) undergoes significant changes in conformation and dynamics upon binding to DPC micelles (2002) Journal of Molecular Biology, 322 (5), pp. 1117-1133.

Pospisil, P., Pilger, B.D., Marveggio, S., Schelling, P., Wurth, C., Scapozza, L., Folkers, G., Pongracic, M., Mintas, M., Malic, S.R. Synthesis, kinetics, and molecular docking of novel 9-(2-hydroxypropyl)purine nucleoside analogs as ligands of herpesviral thymidine kinases (2002) Helvetica Chimica Acta, 85 (10), pp. 3237-3250.

Dahinden, A., Schmidt, R., Folkers, G. Pathways to a new pharmaceutical total quality [Wege zu einer neuen pharmazeutischen, total quality] (2002) Pharmazeutische Industrie, 64 (12), pp. 1233-1238.

Kratz, F., Warnecke, A., Scheuermann, K., Stockmar, C., Schwab, J., Lazar, P., Drückes, P., Esser, N., Drevs, J., Rognan, D., Bissantz, C., Hinderling, C., Folkers, G., Fichtner, I., Unger, C. Probing the cysteine-34 position of endogenous serum albumin with thiol-binding doxorubicin derivatives. Improved efficacy of an acid-sensitive doxorubicin derivative with specific albumin-binding properties compared to that of the parent compound (2002) Journal of Medicinal Chemistry, 45 (25), pp. 5523-5533.

2001

Reinelt, S., Dédier, S., Asuni, G., Folkers, G., Rognan, D. Mutation of Cys-67 Alters the Thermodynamic Stability of the Human Leukocyte Antigen HLA-B*2705 (2001) Journal of Biological Chemistry, 276 (21), pp. 18472-18477.

Rognan, D., Mukhija, S., Folkers, G., Zerbe, O. NMR-restrained docking of a peptidic inhibitor to the N-terminal domain of the phosphoenolpyruvate: Sugar phosphotransferase enzyme I (2001) Journal of Computer-Aided Molecular Design, 15 (2), pp. 103-115.

Wurth, C., Kessler, U., Vogt, J., Schulz, G.E., Folkers, G., Scapozza, L. The effect of substrate binding on the conformation and structural stability of Herpes simplex virus type 1 thymidine kinase (2001) Protein Science, 10 (1), pp. 63-73.

Zhou, X., Gonnet, G., Hallett, M., Münchbach, M., Folkers, G., James, P. Cell fingerprinting: An approach to classifying cells according to mass profiles of digests of protein extracts (2001) Proteomics, 1 (5), pp. 683-690.

Sulpizi, M., Schelling, P., Folkers, G., Carloni, P., Scapozza, L. The rational of catalytic activity of herpes simplex virus thymidine kinase. A combined biochemical and quantum chemical study (2001) Journal of Biological Chemistry, 276 (24), pp. 21692-21697.

Reinelt, S., Marti, M., Dédier, S., Reitinger, T., Folkers, G., López De Castro, J.A., Rognan, D. β-Amino Acid Scan of a Class I Major Histocompatibility Complex-restricted Alloreactive T-cell Epitope (2001) Journal of Biological Chemistry, 276 (27), pp. 24525-24530.

Schelling, P., Folkers, G., Scapozza, L. A spectrophotometric assay for quantitative determination of kcat of herpes simplex virus type 1 thymidine kinase substrates (2001) Analytical Biochemistry, 295 (1), pp. 82-87.

Dédier, S., Reinelt, S., Rion, S., Folkers, G., Rognan, D. Use of overlapping peptide mixtures as antigens for cytokine flow cytometry (2001) Journal of Immunological Methods, 255 (1-2), pp. 27-40.

Wurth, C., Thomas, R.M., Folkers, G., Scapozza, L. Folding and self-assembly of herpes simplex virus type 1 thymidine kinase (2001) Journal of Molecular Biology, 313 (3), pp. 657-670.

Demuth, C., Zerbe, O., Rognan, D., Söll, R., Beck-Sickinger, A., Folkers, G., Spichiger, U.E. A rationally designed oligopeptide shows significant conformational changes upon binding to sulphate ions (2001) Biosensors and Bioelectronics, 16 (9-12), pp. 783-789.

Cavalli, A., Dezi, C., Folkers, G., Scapozza, L., Recanatini, M. Three-dimensional model of the cyclin-dependent kinase 1 (CDK1): Ab initio active site parameters for molecular dynamics studies of CDKs (2001) Proteins: Structure, Function and Genetics, 45 (4), pp. 478-485.

Folkers, G., Klein, C.D.P. Computational methods facilitate the assignment of protein functions (2001) Angewandte Chemie – International Edition, 40 (22), pp. 4175-4177.

2000

Amrhein, I., Wurth, C., Bohner, T., Hofbauer, R., Folkers, G., Scapozza, L. Highly purified recombinant varicella zoster virus thymidine kinase is a homodimer (2000) Protein Expression and Purification, 18 (3), pp. 338-345.

Folkers, G. Pharmaceutica Acta Helvetiae: Editorial (2000) Pharmaceutica Acta Helvetiae, 74 (4), .

Perozzo, R., Jelesarov, I., Bosshard, H.R., Folkers, G., Scapozza, L. Compulsory order of substrate binding to herpes simplex virus type 1 thymidine kinase: A calorimetric study (2000) Journal of Biological Chemistry, 275 (21), pp. 16139-16145.

Dédier, S., Reinelt, S., Reitinger, T., Folkers, G., Rognan, D. Thermodynamic stability of HLA-B*2705-peptide complexes: Effect of peptide and major histocompatibility complex protein mutations (2000) Journal of Biological Chemistry, 275 (35), pp. 27055-27061.

Zhou, X., Alber, F., Folkers, G., Gonnet, G.H., Chelvanayagam, G. An analysis of the helix-to-strand transition between peptides with identical sequence (2000) Proteins: Structure, Function and Genetics, 41 (2), pp. 248-256.

Vogt, J., Perozzo, R., Pautsch, A., Prota, A., Schelling, P., Pilger, B., Folkers, G., Scapozza, L., Schulz, G.E. Nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography (2000) Proteins: Structure, Function and Genetics, 41 (4), pp. 545-553.

Reto, B., Lerch, M., Folkers, G., Zerbe, O. Using structural information of peptides, derived from NMR spectroscopy, in pharmaceutical chemistry (2000) Chimia, 54 (11), pp. 627-632.

Scapozza, L., Ballmer, P., Johner, R., Perozzo, R., Pilger, B., Pospisil, P., Prota, A., Schelling, P., Spadola, L., Wurth, C., Folkers, G. Extended substrate acceptance of Herpes simplex virus type 1 thymidine kinase: A new chance for gene and antiviral therapy (2000) Chimia, 54 (11), pp. 663-668.

Bissantz, C., Folkers, G., Rognan, D. Protein-based virtual screening of chemical databases. 1. Evaluation of different docking/scoring combinations (2000) Journal of Medicinal Chemistry, 43 (25), pp. 4759-4767.

1999

Eberle, A.N., Pliska, V., Burgisser, E., Folkers, G. Special issue on the 8th Swiss Workshop of Methodology in Receptor Research: Preface (1999) Journal of Receptor and Signal Transduction Research, 19 (1-4), pp. xvii-xviii.

Gademann, K., Jaun, B., Seebach, D., Perozzo, R., Scapozza, L., Folkers, G. Temperature-dependent NMR and CD spectra of β-peptides: On the thermal stability of β-peptide helices – Is the folding process of β-peptides non- cooperative? (1999) Helvetica Chimica Acta, 82 (1), pp. 1-11.

Christians, F.C., Scapozza, L., Crameri, A., Folkers, G., Stemmer, W.P.C. Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling (1999) Nature Biotechnology, 17 (3), pp. 259-264.

Dédier, S., Krebs, S., Lamas, J.R., Poenaru, S., Folkers, G., López De Castro, J.A., Seebach, D., Rognan, D. Structure-based design of nonnatural ligands for the HLA-B27 protein (1999) Journal of Receptor and Signal Transduction Research, 19 (1-4), pp. 645-657.

Gonser, S., Crompton, N.E.A., Weber, P.J.A., Beck-Sickinger, A.G., Folkers, G. TP5 triggers signal transduction involving mitogen activated protein kinases in monocytes (1999) Journal of Receptor and Signal Transduction Research, 19 (1-4), pp. 155-166.

Gonser, S., Stalder, J., Folkers, G. Vaccines and their transfection potency (1999) Vaccine, 17 (17), pp. 2113-2116.

Kussmann-Gerber, S., Wurth, C., Scapozza, L., Pilger, B.D., Pliška, V., Folkers, G. Interaction of the recombinant Herpes Simplex Virus type 1 thymidine kinase with thymidine and aciclovir: A kinetic study (1999) Nucleosides and Nucleotides, 18 (3), pp. 311-330.

Weber, P.J.A., Eckhard, C.P., Gonser, S., Otto, H., Folkers, G., Beck-Sickinger, A.G. On the role of thymopoietins in cell proliferation. Immunochemical evidence for new members of the human thymopoietin family (1999) Biological Chemistry, 380 (6), pp. 653-660.

Gonser, S., Weber, E., Folkers, G. Peptides and polypeptides as modulators of the immune response: Thymopentin – An example with unknown mode of action (1999) Pharmaceutica Acta Helvetiae, 73 (6), pp. 265-273

Poenaru, S., Lamas, J.R., Folkers, G., De Castro, J.A.L., Seebach, D., Rognan, D. Nonapeptide analogues containing (R)-3-hydroxybutanoate and β- homoalanine oligomers: Synthesis and binding affinity to a class I major histocompatibility complex protein (1999) Journal of Medicinal Chemistry, 42 (13), pp. 2318-2331.

Alber, F., Folkers, G., Carloni, P. Dimethyl Phosphate: Stereoelectronic versus Environmental Effects (1999) Journal of Physical Chemistry B, 103 (29), pp. 6121-6126.

Muszynski, I.C., Scapozza, L., Kovar, K.-A., Folkers, G. Quantitative structure-activity relationships of phenyltropanes as inhibitors of three monoamine transporters: Classical and CoMFA studies (1999) Quantitative Structure-Activity Relationships, 18 (4), pp. 342-353.

Alber, F., Folkers, G., Carloni, P. Conformational analysis of dimethyl phosphate in aqueous solution: A density functional theory-based molecular dynamics study (1999) Journal of Molecular Structure: THEOCHEM, 489 (2-3), pp. 237-245.

Pilger, B.D., Perozzo, R., Alber, F., Wurth, C., Folkers, G., Scapozza, L. Substrate diversity of herpes simplex virus thymidine kinase. Impact of the kinematics of the enzyme (1999) Journal of Biological Chemistry, 274 (45), pp. 31967-31973.

1998

Hugo Kubinyi, Gerd Fokers and Yvonne C. Martin, 3D QSAR in Drug Design. Recent Advances. Kluwer/Escom, Boston 1998

Hugo Kubinyi, Gerd Fokers and Yvonne C. Martin, 3D QSAR in Drug Design. Ligand-Protein Interactions and Molecular Siminlarity. Kluwer/Escom, Boston 1998

Weber, P.J.A., Bader, J.E., Folkers, G., Beck-Sickinger, A.G. A fast and inexpensive method for N-terminal fluorescein-labeling of peptides (1998) Bioorganic and Medicinal Chemistry Letters, 8 (6), pp. 597-600.

Zbinden, P., Dobler, M., Folkers, G., Vedani, A. PrGen: Pseudoreceptor modeling using receptor-mediated ligand alignment and pharmacophore equilibration (1998) Quantitative Structure-Activity Relationships, 17 (2), pp. 122-130.

Alber, F., Kuonen, O., Scapozza, L., Folkers, G., Carloni, P. Density functional studies on herpes simplex virus type 1 thymidine kinase-substrate interactions: The role of Tyr-172 and Met-128 in thymine fixation (1998) Proteins: Structure, Function and Genetics, 31 (4), pp. 453-459.

Kussmann-Gerber, S., Kuonen, O., Folkers, G., Pilger, B.D., Scapozza, L. Drug resistance of herpes simplex virus type 1 – Structural considerations at the molecular level of the thymidine kinase (1998) European Journal of Biochemistry, 255 (2), pp. 472-481.

Krebs, S., Lamas, J.R., Poenaru, S., Folkers, G., López De Castro, J.A., Seebach, D., Rognan, D. Substituting nonpeptidic spacers for the T cell receptor-binding part of class I major histocompatibility complex-binding peptides (1998) Journal of Biological Chemistry, 273 (30), pp. 19072-19079.

Krebs, S., Folkers, G., Rognan, D. Binding of rationally designed non-natural peptides to the human leukocyte antigen HLA-B*2705 (1998) Journal of Peptide Science, 4 (6), pp. 378-388.

Camenisch, G., Alsenz, J., Van De Waterbeemd, H., Folkers, G. Estimation of permeability by passive diffusion through Caco-2 cell monolayers using the drugs‘ lipophilicity and molecular weight (1998) European Journal of Pharmaceutical Sciences, 6 (4), pp. 313-319.

Camenisch, G., Alsenz, J., van de Waterbeemd, H., Folkers, G. Estimation of permeability by passive diffusion through Caco-2 cell monolayers using the drugs‘ lipophilicity and molecular weight. (1998) European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 6 (4), pp. 317-324.

Camenisch, G., Folkers, G., Van De Waterbeemd, H. Shapes of membrane permeability-lipophilicity curves: Extension of theoretical models with an aqueous pore pathway (1998) European Journal of Pharmaceutical Sciences, 6 (4), pp. 321-329.

Van De Waterbeemd, H., Camenisch, G., Folkers, G., Chretien, J.R., Raevsky, O.A. Estimation of blood-brain barrier crossing of drugs using molecular size and shape, and H-bonding descriptors (1998) Journal of Drug Targeting, 6 (2), pp. 151-165.

Scapozza, L., Folkers, G. Molecular mechanisms governing drug resistance of herpes simplex virus type I linked to thymidine kinase mutations (1998) International Antiviral News, 6 (11), pp. 210-213.

Seebach, D., Poenaru, S., Folkers, G., Rognan, D. Synthesis of Oligo(3-hydroxybutanoate)(OHB)-Containing Peptides with High Binding Affinity to a Class-I-MHC Protein (1998) Helvetica Chimica Acta, 81 (7), pp. 1181-1200.

1997

Han van de Waterbeemd, Bernard Testa, Gerd Folkers, Computer-Assisted Lead Finding. Current Tools for Medicinal Chemistry. Wiley-VCH 1997

Eberle, A.N., Folkers, G., Pliska, V., Burgisser, E. 7th Swiss Workshop of Methodology in Receptor Research: Preface (1997) Journal of Receptor and Signal Transduction Research, 17 (1-3), pp. xvii-xix.

Folkers, G., Alber, F., Amrhein, I., Behrends, H., Bohner, T., Gerber, S., Kuonen, O., Scapozza, L. Integrated homology modelling and x-ray study of herpes simplex virus I thymidine kinase: A case study (1997) Journal of Receptor and Signal Transduction Research, 17 (1-3), pp. 475-494.

Camenisch, G., Folkers, G., Van De Waterbeemd, H. Comparison of passive drug transport through Caco-2 cells and artificial membranes (1997) International Journal of Pharmaceutics, 147 (1), pp. 61-70.

Michael, M., Gerber, S., Fetzer, J., Folkers, G. Oligonucleotide-directed mutagenesis and subsequent expression of the corresponding recombinant proteins without changing the bacterial vector system (1997) Pharmaceutica Acta Helvetiae, 72 (3), pp. 139-143.

Wild, K., Bohner, T., Folkers, G., Schulz, G.E. The structures of thymidine kinase from Herpes simplex virus type 1 in complex with substrates and a substrate analogue (1997) Protein Science, 6 (10), pp. 2097-2106.

Rognan, D., Krebs, S., Kuonen, O., Lamas, J.R., López De Castro, J.A., Folkers, G. Fine specificity of antigen binding to two class I major histocompatibility proteins (B*2705 and B*2703) differing in a single amino acid residue (1997) Journal of Computer-Aided Molecular Design, 11 (5), pp. 463-478.

Behrends, H.W., Folkers, G., Beck-Sickinger, A.G. A new approach to secondary structure evaluation: Secondary structure prediction of porcine adenylate kinase and yeast guanylate kinase by CD spectroscopy of overlapping synthetic peptide segments (1997) Biopolymers, 41 (2), pp. 213-231

Schmetzer, S., Greenidge, P., Kovar, K.-A., Schulze-Alexandru, M., Folkers, G. Structure-activity relationships of cannabinoids: A joint CoMFA and pseudoreceptor modelling study (1997) Journal of Computer-Aided Molecular Design, 11 (3), pp. 278-292.

1996

Gerber, S., Folkers, G. A new method for quantitative determination of tritium-labeled nucleoside kinase products adsorbed on DEAE-cellulose (1996) Biochemical and Biophysical Research Communications, 225 (1), pp. 263-267.

Behrends, H.W., Beck-Sickinger, A.G., Folkers, G. Evaluation of the secondary structure of vaccinia-virus thymidine kinase by circular-dichroism spectroscopy of overlapping synthetic peptides (1996) European Journal of Biochemistry, 241 (1), pp. 126-132.

Camenisch, G., Folkers, G., Van De Waterbeemd, H. Review of theoretical passive drug absorption models: Historical background, recent developments and limitations (1996) Pharmaceutica Acta Helvetiae, 71 (5), pp. 309-327..

Van Waterbeemd, H.D., Camenisch, G., Folkers, G., Raevsky, O.A. Estimation of Caco-2 cell permeability using calculated molecular descriptors (1996) Quantitative Structure-Activity Relationships, 15 (6), pp. 480-490.

Kern, P., Brunne, R.M., Rognan, D., Folkers, G. A pseudo-particle approach for studying protein-ligand models truncated to their active sites (1996) Biopolymers, 38 (5), pp. 619-637.

Czaplicki, J., Bohner, T., Habermann, A.-K., Folkers, G., Milon, A. A transferred NOE study of a tricyclic analog of acyclovir bound to thymidine kinase (1996) Journal of Biomolecular NMR, 8 (3), pp. 261-272.

1995

Folkers, G., Prota, A., Merz, A. Modelling of guanine-derivative – Protein interaction complexes as a basis of drug design (1995) Farmaco, 50 (6), pp. 449-454.

Beck-Sickinger, A.G., Kiess, M., Kern, P., Folkers, G. Secondary structure prediction of adenylate kinase by circular dichroism spectroscopy of synthetic peptides (1995) Pharmaceutica Acta Helvetiae, 70 (1), pp. 33-41.

Fenner, H., Taylor, D., Schattenkirchner, M., Folkers, G., Zueger, S. Immunogenetic profiles correlate with pro-MMP expression in rheumatoid arthritis (1995) Acta Orthopaedica Scandinavica, Supplement, 66 (266), pp. 154-155.

Folkers, G., Michael, M. Pharmacodynamics. New findings about opioids (1995) Schweizer Apothekerzeitung, 133 (9), pp. 214-219.

Wild, K., Bohner, T., Aubry, A., Folkers, G., Schulz, G.E. The three-dimensional structure of thymidine kinase from herpes simplex virus type 1 (1995) FEBS Letters, 368 (2), pp. 289-292.

Rognan, D., Scapozza, L., Folkers, G., Daser, A. Rational design of nonnatural peptides as high-affinity ligands for the HLA-B*2705 human leukocyte antigen (1995) Proceedings of the National Academy of Sciences of the United States of America, 92 (3), pp. 753-757.

Michael, M., Fetzer, J., Folkers, G. Site-directed mutagenesis of Herpes Simplex Virus type 1 thymidine kinase opposes the importance of amino acid positions 251, 321 and 348 for selective recognition of substrate analogs (1995) Biochemical and Biophysical Research Communications, 209 (3), pp. 966-973.

Kern, P., Rognan, D., Folkers, G. MD simulations in pseudo-particle fluids: Applications to active-site protein complexes (1995) Quantitative Structure-Activity Relationships, 14 (3), pp. 229-241.

Greenidge, P.A., Merz, A., Folkers, G. A pseudoreceptor modelling study of the varicella-zoster virus and human thymidine kinase binding sites (1995) Journal of Computer-Aided Molecular Design, 9 (6), pp. 473-478.

1994

Thibaut, U., Folkers, G., Klebe, G., Kubinyi, H., Merz, A., Rognan, D. Recommendations for CoMFA studies and 3D QSAR publications (1994) Quantitative Structure-Activity Relationships, 13 (1), pp. 1-3.

Folkers, G. Modelling of ligand-protein interaction complexes as a basis of drug design (1994) European Journal of Pharmaceutical Sciences, 2 (1-2), pp. 31-33.

Folkers, G. Antifungal agents: New structures and molecular mechanisms (1994) Pharmazeutische Zeitung, 139 (4), pp. 9-12+14+16

Rupp, A., Kovar, K.-A., Beuerle, G., Ruf, C., Folkers, G. A new pharmophoric model for 5-HT reuptake-inhibitors: Differentiation of amphetamine analogues (1994) Pharmaceutica Acta Helvetiae, 68 (4), pp. 235-244.

Kern, P., Brunne, R.M., Folkers, G. Nucleotide-binding properties of adenylate kinase from Escherichia coli: A molecular dynamics study in aqueous and vacuum environments (1994) Journal of Computer-Aided Molecular Design, 8 (4), pp. 367-388.

Folkers, G. Genetic engineering and biotechnology, the future of making drugs? (1994) Pharmaceutica Acta Helvetiae, 69 (1), p. 1.

Folkers, G. Molecular modeling and computer aided drug design 1992/93 – A review (1994) Pharmazie, 49 (8), pp. 551-561.

Fetzer, J., Michael, M., Bohner, T., Hofbauer, R., Folkers, G. A fast method for obtaining highly pure recombinant herpes simplex virus type 1 thymidine kinase (1994) Protein Expression and Purification, 5 (5), pp. 432-441.

Folkers, G., Michael, M. Pharmacodynamics of opioids: Recent developments (1994) Pharmaceutica Acta Helvetiae, 69 (2), pp. 61-68.

Colombel, J., Eger, K., Folkers, G. ModAnE: MODelling of ANistropic effects (1994) Pharmaceutica Acta Helvetiae, 69 (2), pp. 69-75.

Michael, M., Fetzer, J., Folkers, G. Site-directed mutagenesis clarifies the substrate position within the three-dimensional model of the active site of herpes simplex virus type-1 thymidine kinase (1994) European Journal of Biochemistry, 226 (1), pp. 219-226.

Orjala, J., Wright, A.D., Behrends, H., Folkers, G., Sticher, O., Rüegger, H., Rali, T. Cytotoxic and antibacterial dihydrochalcones from Piper aduncum (1994) Journal of Natural Products, 57 (1), pp. 18-26.

Barnett, Y.A., Eger, K., Eriksson, S., Folkers, G., Hansen, P.E., Hofbauer, R., Komitowsky, D., Milor, A., Munch-Petersen, B. Gene technology-based antimetabolite design: The use of an in vitro protein expression system to facilitate antimetabolite design for virally-induced human diseases and malignant conditions (1994) Biotechnology Advances, 12 (4), pp. 663-668.

1993

Rognan, D., Folkers, G. Antigen recognition of viral peptides (1993) Deutsche Apotheker Zeitung, 133 (28), pp. 26-28.

Fetzer, J., Folkers, G., Muller, I., Keil, G.M. Site-directed mutagenesis in the active site of the herpes simplex virus type 1 thymidine kinase gene (1993) Virus Genes, 7 (2), pp. 205-209.

Michael, M., Folkers, G. Biological antifreeze agents in fishes, frogs, flies and spruces (1993) Pharmazie in Unserer Zeit, 22 (1), pp. 25-32.

Folkers, G., Brunjes, J., Michael, M., Schill, J. Modelling by homology of the HSV1-TK sequence embedded structural alignment (1993) Journal of Receptor Research, 13 (1-4), pp. 147-162.

Weber, E., Lehmann, H.P., Beck-Sickinger, A.G., Wawrzynczak, E.J., Waibel, R., Folkers, G., Stahel, R.A. Antibodies to the protein core of the small cell lung cancer workshop antigen cluster-w4 and to the leucocyte workshop antigen CD24 recognize the same short protein sequence leucine-alanine-proline (1993) Clinical and Experimental Immunology, 93 (2), pp. 279-285

1992

Krickl, S., Roth, H.J., Folkers, G. Cisapride, A new prokinetic agent? Computer-assistd study on its structure (1992) Deutsche Apotheker Zeitung, 132 (14), pp. 684-689.

Kovar, K.-A., Rupp, A., Folkers, G. A new drug carrier model for selective 5-HT uptake inhibitors: Differentiation of the entactogens of stimulating and hallucinogenic amphetamines (1992) Sucht, 38 (2), p. 119.

Rognan, D., Zimmermann, N., Jung, G., Folkers, G. Molecular dynamics study of a complex between the human histocompatibility antigen HLA-A2 and the IMP58-66 nonapeptide from influenza virus matrix protein (1992) European Journal of Biochemistry, 208 (1), pp. 101-113.

Rognan, D., Reddehase, M.J., Koszinowski, U.H., Folkers, G. Molecular modeling of an antigenic complex between a viral peptide and a class I major histocompatibility glycoprotein (1992) Proteins: Structure, Function and Genetics, 13 (1), pp. 70-85.

Zimmermann, N., Rötzschke, O., Falk, K., Rognon, D., Folkers, G., Rammensee, H.-G., Jung, G. Molecular modeling of the class I human histocompatibility molecule HLA-A2 presenting an allele-specific nonapeptide from influenza matrix protein (1992) Angewandte Chemie (International Edition in English), 31 (7), pp. 886-890.

1991

Folkers, G. The structure and function of glucocorticoids (1991) Pharmazeutische Zeitung, 136 (40), pp. 9-26.

Freund, S., Jung, G., Gutbrod, O., Folkers, G., Gibbons, W.A., Allgaier, H., Werner, R. The solution structure of the lantibiotic gallidermin (1991) Biopolymers, 31 (6), pp. 803-811.

Krug, M., Folkers, G. ADAPTU: Animated dynamics analysis program at Tubingen University (1991) Journal of Molecular Graphics, 9 (2), pp. 119-121+102.

Zimmermann, N., Beck-Sickinger, A.G., Folkers, G., Muller, I., Jung, G. Conformational and epitope mapping of herpes-simplex-virus type-1 thymidine kinase using synthetic peptide segments (1991) European Journal of Biochemistry, 200 (2), pp. 519-528.

Folkers, G., Trumpp-Kallmeyer, S., Gutbrod, O., Krickl, S., Fetzer, J., Keil, G.M. Computer-aided active-site-directed modeling of the Herpes Simplex Virus 1 and human thymidine kinase (1991) Journal of Computer-Aided Molecular Design, 5 (5), pp. 385-404.

Schill, J., Folkers, G., Roth, H.J., Scior, T. Computer-graphical display of molecules. A new educational aid? (1991) Deutsche Apotheker Zeitung, 131 (50), pp. 2659-2663.

1990

Folkers, G. The development of nucleoside analog antivirus agents by means of theoretic methods (1990) Archiv der Pharmazie, 323 (8), pp. 558-559.

Siemion, I.Z., Folkers, G., Szewczuk, Z., Jankowski, A., Kubik, A., Voelter, W. Peptides related to the active fragment of ‚proline rich polypeptide‘, an immunoregulatory protein of the ovine colostrum. Spectroscopic and computer modeling studies (1990) International Journal of Peptide and Protein Research, 36 (6), pp. 506-514.

1989

Muller, C.E., Folkers, G. Adenosine receptor ligands: Drug of the future? (1989) Pharmazie in Unserer Zeit, 18 (3), pp. 65-75.

Krug, M., Folkers, G., Haas, B., Hess, G., Wiesmuller, K.-H., Freund, S., Jung, G. Molecular dynamics of the α-helical epitope of a novel synthetic lipopeptide foot-and-mouth disease virus vaccine (1989) Biopolymers, 28 (1), pp. 499-512.

Folkers, G., Krickl, S., Trumpp, S. Localization of binding-essential regions in thymidine kinases by the study of sequence homologies (1989) Archiv der Pharmazie, 322 (7), pp. 409-413.

Folkers, G., Junginger, G., Muller, C.E., Schloz, U., Eger, K. Synthesis of computer-modelled high-anti-fixed pyrimidine-nucleoside-analogues with potential virostatic and antineoplastic activities (1989) Archiv der Pharmazie, 322 (2), pp. 119-123.

Eger, K., Folkers, G., Beck, R. Feasibility of isolating and purifying thymidine kinases with the use of affinity chromatography [Isolierung und Reinigungsmöglichkeiten von Thymidinkinasen mit Hilfe der Affinitätschromatographie.] (1989) Pharmazie in Unserer Zeit, 18 (2), pp. 43-52..

Folkers, G., Sakahara, K., Schwobel, W., Eger, K. On the development of a model pharmacophore of thymidine kinase dependent antiviral nucleic acid analogues (1989) Archiv der Pharmazie, 322 (7), pp. 395-398.

1987

Folkers, G., Trumpp, S., Eger, K. Sequence homologies in the C-terminal region and structural relationships of the herpes simplex virus thymidine kinases to other thymidine kinases (1987) Medical Science Research, 15 (11), pp. 633-634.

Folkers, G., Krug, M., Trumpp, S. Computer graphic study on models of the molybdenum cofactor of xanthine oxidase (1987) Journal of Computer-Aided Molecular Design, 1 (1), pp. 87-94.

Folkers, G., Trumpp, S. Sequence and structural homologies of the substrate binding site of cellular and viral thymidine kinases to rabbit muscle adenylate kinase (1987) Medical Science Research, 15 (24), pp. 1495-1496.

1986

Folkers, G., Roth, H.J. A synthetic route to potential inhibitors of 5-lipoxygenase, I (1986) Archiv der Pharmazie, 319 (6), pp. 530-537.

Folkers, G. Receptor affinity of xanthine oxidase inhibitors: Structural preconditions [ (1986) Deutsche Apotheker Zeitung, 126 (41), pp. 2243-2247.

1985

Folkers, G., Roth, H.J. A synthetic route to 5-nitrobenzimidazoles with heterocyclic substituents at N-1 (1985) Archiv der Pharmazie, 318 (10), pp. 953-954.

Folkers, G. Occurrence of toxic byproducts in the in-vitro decomposition of α-aminoalcohols (1985) Archiv der Pharmazie, 318 (9), pp.

Folkers, G., Höltje, H.-D. Active site molecular modelling of xanthine oxidase inhibitors with antiinflammatory activity (1985) Journal of Molecular Graphics, 3 (4), pp. 146-150.

1984

Folkers, G., Chang, D.W., Roth, H.J. Hydrolysis of acetylsalicylic acid catalyzed by thiols (1984) Archiv der Pharmazie, 317 (11), pp. 962-964.